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“Since there are no clinical trials evaluating breast conservation therapy versus mastectomy for tumors over 5 centimeters,” breast conservation is still not recommended for that scenario in current guidelines, he added.

Bleicher and his colleagues analyzed data from nearly 5,700 women who had nonmetastatic breast tumors larger than 5 centimeters who had surgery between 1992 and 2009. Nonmetastatic means the tumors had not spread elsewhere in the body.

Of those women, nearly 16 percent had breast conserving lumpectomy and radiation rather than breast removal.

Over a median follow-up of seven years, overall survival and breast-cancer specific survival rates were similar for both groups of women, according to the study published online Oct. 19 in the journalCancer.

Mastectomy May Not Be The Only Option For Large Breast Tumors  was originally published on

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